Alt click on a node connection automatically disconnect it from the other nodes. And there is some nodes which can be easily summoned by pressing a key and clicking at the same time. Like B+click will place a branch, and S+click a sequence.
If you're willing to compile it, Aseprite is a great option as well.
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This is a great tool by Ilya Kuzmichev, which allow you to edit and draw various curve-based shapes.
Ilya Kuzmichev recently released a new little tool for Substance Designer, which allow you to edit and draw various curve-based shapes. These tools have grayscale and color versions. You can purchase this plugin over at Gumroad for $10.
It’s a really interesting toolkit, which allows doing some awesome material experiments.