Alt click on a node connection automatically disconnect it from the other nodes. And there is some nodes which can be easily summoned by pressing a key and clicking at the same time. Like B+click will place a branch, and S+click a sequence.
If you're willing to compile it, Aseprite is a great option as well.
check my website for the latest tips - always updating with new content!
Grab free terracotta tiles created entirely in Substance Designer by Jura Andreev. The pack will help you create a nice scene, so build something and share it with us!
The package includes an organized full source .sbs file and textures.
More information can be found here.
You can use it in your commercial and personal projects for free.
Substance Designer 2018.1