Take a look at this anime-style character showing diverse emotions crafted by 3D Artist Chiharu using Blender's shape keys.
The artist works on facial expressions, creating a set of studies with various emotional states of the character. The WIP images offer an insightful look into the creative process, revealing that the 2D-looking anime-inspired character is actually a carefully crafted 3D model. Have a look at other works from the series: